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These challenges underscore the urgent need for innovative and effective drugs to overcome these shortcomings and provide more effective and tolerable treatments for UC patients

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Due to changes in growth factor expression, reduction in production, reduction in release, capture and excessive degradation (Zeng et al., 2019), transforming growth factor beta (TGF-β) (Zahid et al., 2019), epidermal growth factor (EGF) (Zhou et al., 2015)